Evidence-Based Directory · 12 Key Actives

Ingredients.

The actives that actually move the needle — scored by clinical evidence, mechanism strength, and real-world skin outcomes.

12 actives ranked3,300+ clinical studies reviewedEvidence · Mechanism · Outcome
Gold StandardEssentialStrong EvidenceEmerging

Niacinamide

Vitamin B3

95

/100

Pore minimising · Oil control · Brightening

Best for

Oily, combination, acne-prone

Studies

340+

Gold Standard

Hyaluronic Acid

HA · Sodium Hyaluronate

93

/100

Deep hydration · Plumping · Barrier support

Best for

All skin types, especially dry

Studies

520+

Gold Standard

Retinol

Vitamin A · Retinoic Acid

97

/100

Cell turnover · Anti-ageing · Collagen synthesis

Best for

Ageing, acne-prone, hyperpigmentation

Studies

890+

Gold Standard

Vitamin C

L-Ascorbic Acid · Ascorbyl Glucoside

91

/100

Brightening · Antioxidant · Collagen support

Best for

Dull, uneven, hyperpigmented skin

Studies

610+

Gold Standard

Ceramides

Ceramide NP · AP · EOP

90

/100

Barrier repair · Moisture retention · Calming

Best for

Dry, sensitive, eczema-prone

Studies

280+

Essential

Salicylic Acid

BHA · Salix Alba Bark

92

/100

Oil-soluble exfoliation · Pore clearing · Anti-acne

Best for

Oily, acne-prone, congested pores

Studies

460+

Gold Standard

Glycolic Acid

AHA · Alpha-Hydroxy Acid

88

/100

Surface renewal · Glow · Fine line reduction

Best for

Dull, textured, hyperpigmented skin

Studies

390+

Essential

Peptides

Palmitoyl Tripeptide · Matrixyl

84

/100

Firmness · Collagen signalling · Anti-wrinkle

Best for

Mature, loss of elasticity

Studies

210+

Strong Evidence

Azelaic Acid

Nonanedioic Acid

89

/100

Redness reduction · Anti-acne · Brightening

Best for

Rosacea, acne, post-inflammatory marks

Studies

175+

Strong Evidence

Bakuchiol

Psoralea Corylifolia Seed

79

/100

Retinol-like renewal · Gentle · Antioxidant

Best for

Sensitive skin avoiding retinoids

Studies

48+

Emerging

Zinc Oxide

Mineral UV filter

94

/100

Broad-spectrum UV · Calming · Anti-inflammatory

Best for

Sensitive, acne-prone, post-procedure

Studies

320+

Gold Standard

Tranexamic Acid

TXA

83

/100

Hyperpigmentation · Melasma · Even tone

Best for

Melasma, dark spots, uneven skin tone

Studies

92+

Strong Evidence

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